JJ You
Vice President, Antibody Discovery AP Biosciences
Dr. Jhong-Jhe You is Vice President of Antibody Discovery at AP Biosciences, leading antibody engineering and biologics R&D for novel therapeutic programs. With over 15 years in antibody drug development, he has guided multiple biologics from discovery to IND approval in the US and Australia. His expertise includes antibody engineering, early-stage drug development, and translational research.
Seminars
Wednesday 10th June 2026
T-cube Platform: Enabling Safer & More Effective Next-Generation T-Cell Engagers
2:30 pm
- Outlining how T-cube activates T-cells only in the presence of tumor-associated antigens by leveraging CD137, minimizing off-tumor activation, and reducing the risk of systemic toxicity
- Evaluating how, by avoiding direct CD3 engagement, T-cube significantly lowers the risk of cytokine release syndrome while maintaining strong antitumor activity in solid tumors
- Discussing how the modular T-cube architecture supports multiple bispecific programs -AP203, AP402, and AP601- each targeting distinct tumor biology and high-value indications
